中药资源学部
您所在位置: 首页 > 师资队伍 > 中药资源学部 > 正文
季爱加
发布时间:2019-10-08      来源:       点击:

undefined


教育工作经历

2017/9-至今 广州中医药大学 bat365官网登录 副研究员

2013/9-2016/6 北京协和医学院 药用植物研究所 博士 导师:宋经元

2009/9-2012/7 上海海洋大学 食品学院 硕士 导师:宁喜斌

2005/9-2009/7 海南大学 食品学院 学士

研究方向

1)药用植物功能基因组学;2)药用植物活性成分合成的转录调控机制;


科研课题

1. 广东省自然科学基金面上项目, 项目编号:2022A1515010646, 穿心莲化感物质鉴定及作用机理研究, 2022.012024.1210万元,在研,主持;

2. 国家自然科学基金青年基金,项目编号:82003895,丹参优形优质相关转录因子NAC36的分子机制解析, 2021.012023.1224万元,在研,主持

3. 广东省自然科学基金青年项目,项目编号:2019A1515110594, 茉莉酸介导的SmERF128调控二萜合成分子机制研究, 2020.012022.710万元,结题,主持;

4. 广东省教育厅广东省普通高校青年创新人才项目,项目编号:E1- KFD015181K31AP2/ERF转录因子调控丹参酮合成研究, 2018.012019.125万元,结题,主持;

5.广州中医药大学高水平大学建设杏林人才项目,项目编号:A1-2606-18-414-0292017.092021.0950万元,结题,主持

6. 科技部基础资源调查专项,项目编号:2018FY100700“一带一路”国家传统草药品种本底整理及数据库建设,2019.012023.12, 1000万元,在研,参加。


承担的课程

要承担《本草基因组学》、《中药分子鉴定技术》、《分子生物学》、《分子生药学》、《生物技术制药》和《药用天然产物的生物合成》等课程

代表性研究论文

1. Rui Guan#, Shun Xu#, Zhimei Lu, Lirong Su, Libing Zhang, Wei Sun, Yu Zhang, Chunhong Jiang, Zhongqiu Liu*, Lixin Duan*, Aijia Ji*. Genomic characterization of bZIP transcription factors related to andrographolide biosynthesis in Andrographis paniculata. International Journal of Biological Macromolecules, 2022, 223:1619–1631 doi: 10.1016/j.ijbiomac.2022.10.283

2. Libing Zhang#, Rui Guan#, Guangli Li, Kexin Su, Lixin Duan, Wei Sun, Xiangxiao Meng, Huihua Wan, Sifan Wang, Shilin Chen, Yaolei Mi*, Aijia Ji*. Genomic identification of ARF transcription factors and expression analysis in Cannabis sativa L. Industrial Crops & Products, 2022,186:115118 doi: 10.1016/j.indcrop.2022.115118

3. Guangli Li#, Tianyue An#, Yu Li, Jinyang Yue, Ruoshi Huang, Jia Huang, Jincai Liang, Wei Yao, Liufang Huang, Yidu Chen, Rongrong Zhang, Aijia Ji* and Lixin Duan*. Transcriptome analysis and identification of the cholesterol side chain cleavage enzyme BbgCYP11A1 from Bufo bufo gargarizans. Frontiers in Genetics, 2022,13:828877. doi: 10.3389/fgene.2022.828877.

4. Yunpeng Wang, Wenbo Xiong, Yidu Chen, Min Zhu, Jincai Liang, Yu Li, Jia Huang, Liufang Huang, Zhongqiu Liu, Aijia Ji*, Lixin Duan*. Transcriptomic investigation of the biochemical function of 7-dehydrocholesterol reductase 1 from the traditional Chinese medicinal plant Anemarrhena asphodeloides Bunge. Phytochemistry, 2021,192:112954.

5. Jia Huang, Jing Li, Jingyang Yue, Zilu Huang, Libing Zhang, Wei Yao, Rui Guan, Jianlian Wu, Jincai Liang, Lixin Duan* and Aijia Ji*. Functional characterization of a novel glycosyltransferase (UGT73CD1) from Iris tectorum Maxim. for the substrate promiscuity, Molecular Biotechnology, 2021, 63, 1030–1039. doi: 10.1007/s12033-021-00364-1

6. Rongrong Zhang#, Zhenzhen Chen#, Libing Zhang, Wei Yao, Zhichao Xu, Baosheng Liao, Yaolei Mi, Han Gao, Chunhong Jiang, Lixin Duan* and Aijia Ji* Genomic Characterization of WRKY Transcription Factors Related to Andrographolide Biosynthesis in Andrographis paniculata. Frontiers in Genetics, 2021,11:601689.

7. Wei Yao#, Tianyue An#, Zhichao Xu, Libing Zhang, Han Gao, Wei Sun, Baosheng Liao, Chunhong Jiang, Zhongqiu Liu*, Lixin Duan* and Aijia Ji*. Genomic-wide identification and expression analysis of AP2/ERF transcription factors related to andrographolide biosynthesis in Andrographis paniculata, Industrial Crops & Products, 2020,157. doi: 10.1016/j.indcrop.2020.112878

8. Yu Zhang#, Aijia Ji#, Zhichao Xu, Hongmei Luo, Jingyuan Song*. The AP2/ERF transcription factor SmERF128 positively regulates diterpenoid biosynthesis in Salvia miltiorrhiza. Plant Molecular Biology. 2019, 100 (1-2):83-93. doi: 10.1007/s11103-0 19-00845-7.

9. Aijia Ji#, Jing Jia#, Zhichao Xu, Ying Li, Wu Bi, Fengming Ren, Chunnian He, Jie Liu, Kaizhi Hu*, Jingyuan Song*. Transcriptome-guided Ming of Genes Involved in Crocin Biosynthesis, Frontiers in Plant Science. 2017 8:518. doi: 10.3389/fpls.2017.00518.

10. Aijia Ji, Hongmei Luo, Zhichao Xu, Xin Zhang, Yingjie Zhu, Baosheng Liao, Hui Yao, Jingyuan Song*, Shilin Chen*. Genome-wide identification of the AP2/ERF gene family involved in active constituent biosynthesis in Salvia miltiorrhiza, Plant Genome. 2016 9(2),1-11.

11. Aijia Ji#, Qing Ma#, Muyan Kong#, Leyan Li, Xinlian Chen, Zhongqiu Liu, Jinjun Wu*, Rong-Rong Zhang*. Two cardenolide glycosides from the seed fairs of Asclepias curassavica L. and their cytotoxic activities, Chinese Journal of Natural Medicines. 2022, 20 (2): 1-8. doi: 10.1016/S1875-5364(21)60098-5.

12. Shidan Wu#, Fan Zhang#, Wenbo Xiong, Istvan Molnar, Jincai liang, Aijia Ji, Yu Li, Caixia Wang, Shengliang Wang, Zhongqiu Liu*, Ruibo Wu*, and Lixin Duan*. An Unexpected Oxidosqualene Cyclase Active Site Architecture in the Iris tectorum Multifunctional α-Amyrin Synthase, ACS catalysis. 2020,10(16), 9515–9520.

13. Yu Zhang, Zhichao Xu, Aijia Ji, Hongmei Luo, Jingyuan Song*. Genomic Survey of bZIP Transcription Factor Genes Related to Tanshinone Biosynthesis in Salvia miltiorrhiza [J]. Acta Pharmaceutica Sinica B, 2018, 8(2):295-305.

14. Zhichao Xu, Aijia Ji, Xin Zhang, Jingyuan Song*, Shilin Chen*. Biosynthesis and Regulation of Active Constituents in Medicinal Model Plant Salvia miltiorrhiza. Chinese Herbal Medicines, 2016, 8(1): 3-11.

15. Haibin Xu#, Jingyuan Song#, Hongmei Luo#, Yujun Zhang, Qiushi Li, Yingjie Zhu, Jiang Xu, Ying Li, Chi Song, Bo Wang, Wei Sun, Guoan Shen, Xin Zhang, Jun Qian, Aijia Ji, Zhichao Xu, Xiang Luo, Liu He, Chuyuan Li, Chao Sun, Haixia Yan, Guanghong Cui, Xiwen Li, Xian'en Li, Jianhe Wei, Juyan Liu, Yitao Wang, Alice Hayward, David Nelson, Zemin Ning, Reuben J. Peters, Xiaoquan Qi*, Shilin Chen*, Analysis of the genome sequence of the medicinal plant Salvia miltiorrhiza, Molecular Plant, 2016, 9(6): 949-952.

16. 季爱加, 罗红梅, 徐志超, 张鑫, 宋经元*, 陈士林*. 药用植物转录因子AP2/ERF研究与展望[J]. 科学通报,2015,60(14):1272-1284.

17. 徐江, 孙超, 徐志超, 季爱加, 胡鸢雷, 孙伟, 王丽芝, 汪波, 杨培, 张鑫, 宋经元, 陈士林*. 药用模式生物研究策略[J]. 科学通报,2014,59(9):733-742.


代表性著作

《药用植物分子遗传学》科学出版社 2022 编委

授权专利

1. 段礼新,刘中秋,王丽君,梁锦才,季爱加. 一种源于知母的β-葡萄糖苷酶、其编码基因、表达载体及其应用. 中国,ZL201910216451.12022-03-25.

2. 季爱加,陈珍珍,段礼新,刘中秋,李静,吴世丹,陈义都. 一种丹参转录因子SmNAC78基因及其表达载体的应用. 中国,ZL202011038347.72022-03-08.

3. 段礼新,刘中秋,吴世丹黄柳芳季爱加,梁锦才. 一种用于催化合成香树素的蛋白及其制备方法和应用. 中国,ZL202010622749.5,  2021-12-24.

4. 宋经元,张瑜,季爱加. 一种丹参AP2转录因子SmERF128编码序列及克隆方法与应用. 中国,ZL201810285885.22021-09-21.

5. 罗红梅,张建红,吕海舟,宋经元,季爱加. 一种调控丹参酮生物合成的SmAP2/ERF82转录因子的筛选、鉴定及应用. 中国,ZL201710849664.92021-08-31.

发明专利

1. 季爱加,陈珍珍,段礼新,刘中秋,李静,吴世丹,陈义都. 一种丹参转录因子SmNAC36基因及其应用. 中国,申请号:201910757916.4,申请时间:2019-08-16.

2. 罗红梅,张建红,张鑫,季爱加,吕海舟,宋经元. SmbHLH92 基因克隆引物、表达载体、调控丹酚酸生物合成的功能及应用. 中国,申请号:201910571110.6,申请时间:2019-06-28.

罗红梅,吕海舟,张建红,季爱加. 一种调控丹酚酸生物合成的SmAP2/ERF8转录因子的筛选、鉴定及应用. 中国,申请号:201710849712.4,申请时间:2017-09-20.


上一条:郑夏生

下一条:林 颖


Baidu
sogou